Vasoconstrictors reduce redness and may be used safely for up to 72 hours. Use them once in the morning and once before bedtime. How to UseĪpply eye drops to treat red eyes no more than twice daily. This can cause "rebound redness"-when the drops wear off, blood vessels dilate even larger than they were before, making eyes appear bloodshot. Vasoconstricting eye drops are not popular with eye doctors for treating red eye because, when used for too long, they wear off quickly and prompt too-frequent use. Examples of vasoconstricting eye drops include: Vasoconstrictors (decongestants) work by shrinking the small blood vessels in the conjunctiva. You can resolve or prevent red eyes by avoiding triggers such as lack of sleep, alcohol consumption, smoking, swimming in a chlorinated pool, or, ironically, overusing eye drops to treat the redness. Most often, however, the cause of red eyes is benign (harmless).
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